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This trial compared standard care with standard care plus spinal manipulative therapy (SMT). Conclusions: SMT is unlikely to result in relevant early pain reduction in patients with acute low back pain. Bernhard, H-R Ziswiler, M Dähler, S Reichenbach and P M Villiger P Jüni, M Battaglia, E Nüesch, G Hämmerle, P Eser, R van Beers, D Vils, J, Ann Rheum Dis 2009;68;1420-1427 (originally published online 5th September 2008) [pdf]